Profile

Shukti Chakravarti, PhD

NYU Langone Health

Contact Details


Bio

Current Appointments
Professor of Ophthalmology and Pathology
Director, Basic Science Research Ophthalmology
NYU Langone Health
Primary
Professor, Department of Ophthalmology, NYU Langone Health 

Adjunct 
Professor, Department of Ophthalmology, Wilmer Eye Institute, Johns Hopkins SOM

SELECTED PUBLICATIONS
Chakravarti S, Magnuson T, Lass JH, LaMantia C, Jepsen KJ, Carroll H. Collagen fibril defects affecting skin and cornea in lumican-deficient mice. J Cell Biol. 1998; 141: 1277-1286. PubMed PMID: 9606218;PubMed Central PMCID: PMC2137175.

Chakravarti S, Petroll WM, Hassell JH, Jester J, Lass JH, Paul J, Birk DE. Corneal opacity in lumican-null mice: defects in collagen fibril structure and packing in the posterior stroma. Invest Ophthalmol. Vis. Sci. 2000; 41(11):3365-3373.

Ezura Y, Chakravarti S, Oldberg A, Chervoneva I, Birk DE. Differential expression of lumican and fibromodulin regulate collagen fibrillogenesis in developing mouse tendons. J Cell Biol. 2000 ; 151: 779-787. PubMed Central PMCID: PMC2169450
Chakravarti S, Wu F, Vij N, Roberts L, Joyce S. Microarray studies reveal macrophage-like function of stromal keratocytes in the cornea. Invest Ophthalmol Vis Sci. 2004; 45:3475-84. PubMed PMID: 15452052.

Vij N, Roberts L, Joyce S, Chakravarti S. Lumican regulates corneal inflammatory responses by modulating Fas-Fas ligand signaling. Invest Ophthalmol Vis Sciences. 2005; 46: 88- 95. PubMed PMID: 15623759.

Beecher N, Chakravarti S, Joyce S, Meek KM, Quantock AJ. Neonatal development of the corneal stroma in wild-type and lumican-null mice. Invest Ophthalmol Vis Sci. 2006; 47:146-50. PubMed PMID: 16384956.

Chakravarti S, Zhang G, Chervoneva I, Roberts L, Birk D. Collagen fibril assembly during postnatal development and dysfunctional regulation in the lumican-deficient murine cornea. Dev Dyn. 2006; 235:2493-2506. PubMed PMID: 16786597.

Shao, H, Chaerkady, R, Chen, S, Sneha, Pintoc, M, Sharma, R, Delanghe,B, Birk, D, Pandey, A and Chakravarti, S. Proteome profiling of wild type and lumican-deficient mouse corneas. J Proteomics. 2011 May 17. [Epub ahead of print] PMID: 21616181 PMCID: 3163732.

Scott S-G, Jun AS and Chakravarti S. Sphere formation from corneal keratocytes and phenotype specific markers. Experimental Eye Research, 2011 Dec;93(6):898-905. Epub 2011 Oct 21. PMID: 22032988 PMCID: 3225580.

Foster J, Wu WH, Scott SG, Bassi M, Mohan D, Daoud Y, Stark WJ, Jun AS, Chakravarti S. Transforming growth factor β and insulin signal changes in stromal fibroblasts of individual keratoconus patients. PLoS One. 2014 Sep 23;9(9):e106556. doi: 10.1371/journal.pone.0106556. eCollection 2014. PubMed PMID: 25247416; PubMed Central PMCID: PMC4172437.

Gowda RN, Redfern R, Frikeche J, Pinglay S, Foster JW, Lema C, Cope L, Chakravarti S. Functions of Peptidoglycan Recognition Proteins (Pglyrps) at the Ocular Surface: Bacterial Keratitis in Gene-Targeted Mice Deficient in Pglyrp-2, -3 and -4. PLoS One. 2015 Sep 2;10(9):e0137129. doi:10.1371/journal.pone.0137129. eCollection 2015. PubMed PMID: 26332373; PubMed Central PMCID: PMC4558058.