Types and design of clinical trials
Evaluation of the risk-benefit ratio, as well as review and approval of the study protocol and other documentation related to the conduct of clinical trials, are the responsibility of the Expert Council of the Organization / Independent Ethics Committee (EEC / IEC). Once approval has been received from the ESO/NEC, the clinical trial can be initiated.
There are several types of clinical trials:
1. Pilot study
2. A randomized clinical trial
3. Controlled and uncontrolled
4. Parallel and cross-over studies
5. Open and blind studies
6. Prospective
7. Single-center and multicenter
8. Cohort
9. Case-control study
All clinical trials are classified according to certain characteristics: purpose, duration of time, presence of intervention in the usual tactics of patient management, etc.
Studies by purpose:
- Preventive studies to find the best ways to prevent disease in people who have never had onlineessaywriter.co , or to prevent recurrence of disease in patients;
- Screening studies - finding the best ways to detect certain diseases or conditions;
- Diagnostic studies - looking for ways to diagnose a certain disease or condition;
- Therapeutic studies are conducted to study the effectiveness and safety of experimental drugs, new drug combinations, or new methods in surgery or radiation therapy;
- Quality of life research is conducted to explore paper help ways to improve the quality of life of patients with chronic conditions;
- Extended access programs (exceptionally involving the use of an experimental drug in patients with serious or life-threatening conditions who cannot be included in a clinical trial because they do not meet the inclusion criteria.
Studies on the presence of interference in the usual tactics of patient management (in the standard procedures of examination and treatment of the patient):
- Observational (observational) study - a clinical study in which the investigator collects data by do my essay, simply observing events in their natural course without actively intervening in them;
- non-interventional study ("non-intervention study") - a study in which a drug is administered in the usual way in accordance with the conditions set forth in the marketing authorization.
- interventional study - a study of new, unregistered medicinal products, immunobiological agents, medical devices, or a study in which a medicinal product, immunobiological agent, or medical device is prescribed or administered in a manner different from the conditions set forth in the registered instructions (whether a new indication, new dose of the product, new route of administration, new route of administration or a new patient category).
Studies by observation time interval:
- Retrospective (historical) study - A study that examines the outcomes of previous clinical trials or freeessaywriter, that is, the outcomes have already occurred before the study began. The researcher reviews medical records and selects patients according to certain criteria in order to study treatment outcomes.
- Prospective study - a study in which patients are recruited according to the criteria set out in the study protocol.
Patients receive the study drug and are followed for a period of time. The formation of groups receiving or not receiving the study drug takes place before the results are recorded. Most clinical trials are prospective.
More resources:
Joe Neil’s Gallery
How to improve your writing skills
Freelance Writer
Tips for improving your essay