Profile

Enrica Strettoi, PhD

CNR Neuroscience Institute

Contact Details


Bio

PERSONAL INFORMATION
Family name, First name: Strettoi, Enrica
Nationality: Italian
URL for web site: http://www.in.cnr.it/index.php/en/joomlaorg-2/pisa-en/people-pi/168-enrica-en


• AWARDS
2016 International Collaborative Research Award (IRCA), University of Sydney, Australia. COllaborative research project at Save Sight Institute, Sydney (Dr. Ulrike Grunert)
2011 Recognition for “Outstanding contribution to the field of vision research”, Emory Eye Center, Emory University, Atlanta, USA

• SUPERVISION OF GRADUATE STUDENTS AND POSTDOCTORAL FELLOWS
2015-present Thesis advisor and scientific tutor. Antonia Stefanov, Early Stage Researcher, Switchboard Project funded under a Marie Curie, Horizon2020 ETN action/ i/PhD student in Neuroscience, Regional Doctorate School in Neuroscience PhD course/Universities of Florence, Pisa and Siena/Italy
2015-present Thesis advisor. Martina Biagionii/PhD student in Neuroscience, Regional Doctorate School in Neuroscience PhD course/Universities of Florence, Pisa and Siena/Italy
2010 – 2015 Thesis advisor. Viviana Guadagni/PhD student in BIOS, Molecular Biotechnologies PhD course/University of Pisa/Italy
20013 – 20014 Thesis advisor. Miruna Ghinia/PhD student in Biology, Faculty of Science/ University of Cluj-Napoca/Romania
2000 – 2013 Thesis advisor (mentor) of the following PhD students: V. Pignatelli (PhD in Neuroscience); C. Rossi (PhD in Clinical Biochemistry); F. Mazzoni and D. Damiani (PhDs in Molecular Biotechnologies); Co-tutor of three students in Neuroscience (M. Calamusa; E. Terzibasi; P. Lonetti), all from the University of Pisa.
• TEACHING ACTIVITIES (recent)
2014-present; 2004 – 2005/ Professor of Neurobiology/Faculty of Science/ University of Pisa, Italy
2004/2006/2008/2010 Faculty Member of the international summer course “Fundamental issues in vision research”, Marine Biological Laboratories, Woods Hole, USA.
1999 – 2000/2000 - 2001 Professor of Physiology/ Faculty of Pharmacy/University of Pisa, Italy

• ORGANISATION OF SCIENTIFIC MEETINGS
2007 Co-organizer. Advanced school of microscopy. CNR, Pisa, ITALY.
2010 Co-organizer. 16th Retina International World Conference, Stresa, Italy
2011 Co-organizer. ERM, international European Retina Meeting, Amsterdam, Nederland’s

• INSTITUTIONAL RESPONSIBILITIES
1999 - 2013 Faculty member, Doctoral course in Neuroscience, University of Pisa
2000 – 2005 Responsible for animal experimentation, Institute of Neurophysiology/Neuroscience/Italian National Research Council (CNR), Pisa/Italy
2005 – 2014 Director Delegate, Head of the Pisa site of the Institute. Institute of Neuroscience/ Department of Biomedical Sciences/ Italian National Research Council (CNR), Pisa/Italy

2013 – present Faculty member, Regional Doctoral School in Neuroscience, University of Florence
2000 – present Organizer of internal Seminars with international speakers, CNR Neuroscience Institute, Pisa/Italy
2000 – present Member of various Committees for the recruitment of research fellows or junior members,CNR Neuroscience Institute, Pisa/Italy

• COMMISSIONS OF TRUST (selection)

2014 – present Editorial board member, The Journal of Comparative Neurology, Wiley-LISS, USA
2014 - present Editorial board member, Frontiers in Neuroanatomy
2011 – present Editorial board member, Molecular Vision, USA
2013 - Member, International search committee, selection of European Research Award recipient
2010 - Scientific evaluator, advanced ERC research award, EU
2009 – Member, International search committee, search for full Professor in Ophthalmic Research/Head of a research center, University of Tuebingen, Germany
2009 – Candidate evaluator, position of Assistant Professor, Department of Ophthalmology, Harvard Medical Scool/Boston/USA
2005 – Scientific evaluator, grant proposals The Netherlands Organization for Health Research and Development (ZonMw), The Netherlands
2005 – Scientific evaluator, grant proposals, Wellcome Trust, England

• MEMBERSHIPS OF SCIENTIFIC SOCIETIES
Member/Association of Research for Vision and Ophthalmology (ARVO)/USA,

• MAJOR COLLABORATIONS

• William Hauswirth. Phenotype study of animal models of inherited photoreceptor degeneration before and after gene therapy. University of Florida, Department of Ophthalmology, USA.
• Gianluca Tosini- Melatonin role in retinal physiology. Circadian Rhythms and Sleep Disorders Program, Neuroscience Institute, Department of Anatomy & Neurobiology, Morehouse School of Medicine, Atlanta, USA.
• Claudia Gargini. Anatomy and physiology of animal models of retinal degeneration. Department of Pharmacy, University of Pisa, Italy.
• Riccardo Ghidoni. Pharmacological treatments for photoreceptor degeneration. San Paolo Medical School, University of Milan, Italy.

Enrica Strettoi Ten years track-record (SYNTHESIS)

1. FIVE representative publications, as senior author (source: ISI Web of Science)
• Damiani D, Novelli E, Mazzoni F, Strettoi E. Undersized dendritic arborizations in retinal ganglion cells of the rd1 mutant mouse: a paradigm of early onset photoreceptor degeneration. J Comp Neurol. 2012 May 1;520(7):1406-23. doi: 10.1002/cne.22802.
• Strettoi E, Gargini C, Novelli E, Sala G, Piano I, Gasco P, Ghidoni R. Inhibition of ceramide biosynthesis preserves photoreceptor structure and function in a mouse model of retinitis pigmentosa. Proc Natl Acad Sci U S A. 2010 Oct 26;107(43):18706-11. doi: 10.1073/pnas.1007644107.
• Damiani D, Alexander JJ, O'Rourke JR, McManus M, Jadhav AP, Cepko CL, Hauswirth WW, Harfe BD, Strettoi E. Dicer inactivation leads to progressive functional and structural degeneration of the mouse retina. J Neurosci. 2008 May 7;28(19):4878-87. doi: 10.1523/JNEUROSCI.0828-08.2008.
• Gargini C, Terzibasi E, Mazzoni F, Strettoi E. Retinal organization in the retinal degeneration 10 (rd10) mutant mouse: a morphological and ERG study. J Comp Neurol. 2007 Jan 10;500(2):222-38. Strettoi E, Mears AJ, Swaroop A. Recruitment of the rod pathway by cones in the absence of rods. J Neurosci. 2004 Aug 25;24(34):7576-82.

2. Research monographs
1. Strettoi E, Parisi V. 2014. “Fundamental retinal circuitry for circadian rythms”. In: The retina and circadian rhythms, Tosini, Iuvone, MacMahon and Collin Eds. Springer Series in Vision Research. pp 3-26. ISBN: 978-1-4614-9612-0.
2. Tosini,m Strettoi E. 2010. “Morphology of interneurons: amacrine cells”. In: Encyclopedia of the Eye, Besharse & Dana Editors;. Vol. 4, pp 60-64.Elsevier, Academic Press ISBN: 9780123741981
3. Strettoi E. Synaptic organization of the mouse retina. In: Eye, Retina, and Visual System of the Mouse. L Chalupa and R Williams editors. MIT Press., 2008. pp-157-164.
4. Strettoi E. Mammalian rod pathways. In: A Basbaum, A Kaneko, G Sheperd, G Westheimer, editors. The Senses: a Comprehensive Reference. Vol.1, Vision I, R Masland and T Albright. San Diego: Academic Press; 2008. pp-303-311.

3. Granted patent (coinventor)
2014: European Patent No. 2400958 “Serine Palmitoyltransferase inhibitors for preventing and delaying retinitis pigmentosa”. Extended to China, Japan, Canada and the USA
https://data.epo.org/publication-server/rest/v1.0/publication-dates/20140423/patents/EP2400958NWB1/document.pdf

4. Invited presentations to peer-reviewed, internationally established conferences and/or international advanced schools (selection)

2015. Opening lecture of the Euroepan Frontiers in Ocular Pharmachology series. University of Catania, Italy.
2013. Invited participant and speaker. Monaciano International Symposium on Retinal Degeneration organized by the Kellogg Eye Center, University of Michigan. Monaciano (Siena), Italy.
2012. Invited participant and speaker. Optogenetics Symposium, organized by the Foundation Fighting Blindness and Harvard Medical School, Boston, USA.
2009. Plenary Lecture. “Inherited retinal degeneration: lessons from basic research”, “European Frontiers in Ocular Pharmacology series”, University of Catania, Italy.


5. Organisation of international conferences in the field (membership in the steering and/or organising committee)
2011. Co-organizer and Speaker. ERM, international European Retina Meeting, Amsterdam, Nederlands.
2010. Co-organizer and Speaker. 16th Retina International World Conference, Stresa, Italy

6. Publication highlights

h-index: 29 (Google Scholar).
Author of 53 peer-reviewed articles; of these: 5 are invited reviews; 2 have been cited >500 times each;4 have been cited >200 times each; 12 have been cited >100 times each; 22 have been cited >50 times each and 5 received a cover picture.