Profile

Dr. Kazuo Tsubota, MD, PhD, FARVO, MBA

CEO,
Tsubota Laboratory, Inc.

Contact Details

Tsubota Laboratory, Inc.
Tsubota Laboratory, Inc.
34 Shinanomachi
304 Toshin Shinanomachi-ekimae Bldg.
Shinjuku-ku Tokyo
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Bio

Kazuo Tsubota is professor emeritus of the Department of Ophthalmology at Keio University School of Medicine, his alma mater. An internationally recognized dry eye specialist, Prof. Tsubota has been working on the pathogenesis and treatment of dry eye for much of his career. Prof. Tsubota was the first Japanese recipient of the American Academy of Ophthalmology Honor Award and is author of more than 700 scientific peer-reviewed articles.

 

As most ocular diseases are related to aging, Prof. Tsubota began to explore the topic of aging in 1999, and currently focuses on aging and anti-aging research, ranging from the molecular level to clinical applications with a focus on prevention of age-related eye diseases such as macular degeneration, glaucoma and dry eye.

 

His latest research activities spotlight myopia due to the myopia boom affecting Japan and East and Southeast Asia. His research focuses on the hypothesis that violet light has a suppressive effect against the progression of myopia and blue light’s role in determining circadian rhythm, mood, and memory. A clinical trial is underway on violet light (VL)-emitting eyeglasses, a product of Tsubota Laboratory, which are commercially available. The VL emitting eyeglasses provide the necessary VL to prevent myopia progression.

 

More recently, Prof. Tsubota is interested in innovation and entrepreneurship and is director of the innovation program at Keio University which encourages researchers to start venture companies based on their scientific findings. To set an example he established his own company, Tsubota Laboratory, a Keio University-launched startup, which focuses on the clinical application of violet light for the control of myopia as well as dry eye. He has successfully designed and marketed moisture glasses for dry eye which are popular in Japan.

 

What motivates him is the desire to contribute to a prosperous and long-lived society, reductions in healthcare costs, and above all, improved health and happiness for individuals.

Education

Harvard Medical School, Massachusetts Eye & Ear Infirmary
Boston, Massachusetts, United States
Clinical and Research Fellowships
1985 To 1987
Advisor: Prof. Claes Dohlman

Keio University School of Medicine
Tokyo, Japan
Residency in Ophthalmology
1980 To 1984

College of Medicine, Keio University
Tokyo, Japan
MD, 1980
1974 To 1980

Keio Business School
Tokyo, Japan
MBA, 2019

Keio University School of Medicine
Tokyo, Japan
PhD, 1999

Job History

Tsubota Laboratory, Inc.
CEO
Tokyo, Japan
February 2015 - present

Tokyo Dental College, Ichikawa General Hospital
Visiting Professor of Ophthalmology
Ichikawa, Japan
April 2004 - March 2021

Keio University School of Medicine
Prof. & Dept Chair
Tokyo, Japan
April 2004 - March 2021

Tokyo Dental College, Ichikawa General Hospital
Director of Ophthalmology
Ichikawa, Japan
March 1990 - March 2004

National Tochigi Hospital
Director of Ophthalmology
Tochigi, Japan
January 1988 - January 1989